منابع مشابه
Histamine release upon adenosine 5'-monophosphate (AMP) nasal provocation in allergic subjects.
BACKGROUND Nasal provocation with adenosine 5'-monophosphate (AMP) elicits nasal symptoms in subjects with rhinitis. Histamine released from mast cells may play a part in AMP induced nasal responses. METHODS Symptoms of rhinitis were recorded and histamine release in the fluid obtained by nasal lavage after AMP, guanosine 5'-monophosphate (GMP), and placebo instillations was measured in nine ...
متن کاملOptical rhinometry in nasal provocation testing
INTRODUCTION Optical rhinometry (ORM) is a technique that allows for direct continuous measurement of changes in blood flow (optical density) in nasal vessels, at the same time analyzing changes per unit of time in the evaluated variable: intravascular blood flow and oxygen saturation. AIM To assess the extent to which ORM can be used as an objective measure of nasal mucosal edema following a...
متن کاملNasal allergen provocation test in nasal polyposis with and without allergy
Methods Four groups of patients (n=48) underwent nasal allergen provocation test for grass pollen. We included 12 patients with allergic rhinitis based on grass allergy, 12 patients with CRSwNP without grass allergy, 12 patients with CRSwNP with grass allergy, and 12 control patients. The diagnosis of grass allergy was based on skin prick test and RAST. The test was positive based on change in ...
متن کاملLeukotriene D4 nasal provocation test: Rationale, methodology and diagnostic value.
Cysteinyl leukotrienes (LT) play a vital role in the pathogenesis of allergic rhinitis (AR), but few studies have investigated the nasal mucosal physiological response to LTs in AR patients. The aim of the present study was to establish the methodology and investigate the diagnostic value and safety of a leukotriene D4 (LTD4) nasal provocation test. LTD4 nasal provocation tests were performed i...
متن کاملSpecificity and sensitivity assessment of selected nasal provocation testing techniques
INTRODUCTION Nasal provocation testing involves an allergen-specific local reaction of the nasal mucosa to the administered allergen. AIM To determine the most objective nasal occlusion assessment technique that could be used in nasal provocation testing. MATERIAL AND METHODS A total of 60 subjects, including 30 patients diagnosed with allergy to common environmental allergens and 30 health...
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ژورنال
عنوان ژورنال: Thorax
سال: 1999
ISSN: 0040-6376
DOI: 10.1136/thx.54.11.1050